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Guillain Barré Syndrome
Introduction & Overview
Guillain-Barre Syndrome is a rare but serious disease affecting the peripheral nervous system in which the bodys own immune system attacks the nerves causing a widespread inflammation leading to tingling and numbing sensation of the limbs (arms and legs) eventually resulting in a short term loss of feeling and movement (temporary paralysis). (1)
Generally, patients suffering from Guillain-Barre Syndrome exhibit absence or a profound delay in conduction by nerve fibers due to demyelination of nerve cell axons causing direct cellular immune attack on the axon leading to its damage. Peripheral nerves and spinal roots are the sites of demyelination (3).
Guillain-Barre syndrome (GBS) occurs at a frequency of 1-2 cases per every 100,000 people annually in the US and can affect any individual regardless of age or sex. (4).
Article by Kona Vishnu, MS
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